Field of Interest:physics.acc-phys
Experiments:Simulation plus experiments at CERN and Daresbury Lab.
Deadline: 2017-08-31
Region: Europe
Job description:
Treatment planning for VHEE (Very High Energy Electron) Scanned Beams
VHEE embraces the energy range 50 – 250 MeV and can deliver doses up to 20-30 Gy per second. Studies by DesRosiers, et al in the early 2000s have shown that VHEE therapy has the potential to be a better, yet cost-effective alternative to the photon therapy. Some potential advantages of this mode of radiotherapy over photon and proton therapy include:
· Better sculpting or conformal mapping –as there are minimal moving parts with electron scanning and beam steering is continuous.
· Rapid dose delivery –reduces necessity of preventing patient motion. In essence, physiological motion is frozen with this method –and indeed freezing the motion to less than one heartbeat should be feasible.
· Potentially better tumour control efficiency for the same dose.
· “Flash” therapy, entailing rapid and high dose delivered with VHEE beams indicates superior cell recovery –compared to that with cells irradiated over longer periods with extant modalities.
· Recent simulations with 15 MeV photons showed significant perturbations of dose around an air cavity in the tissue, whereas simulations with 200 MeV electron beams showed negligibly small perturbations.
VHEE radiotherapy will make a significant impact on treating cancer with radiotherapy and hence will improve the overall quality of life of the people within the UK. The treatment planning envisaged will entails detailed studies with realistic margins considered. It is anticipated to lead to high quality publications in this area, and to pave the way for the potential for a new treatment modality –with significant advantages of extant treatments. In addition to its direct impact on dose delivery studies, it will also have a significant impact on the design of a future linac-based machine for VHEE radiotherapy treatment –with the results of this study providing guidance on the requirement on a the design of a future machine suitable for patient treatment.
In summary, we anticipate major impact from this project in the area of high quality journal publications, cross-disciplinary work, and providing essential input into guiding the design of a future facility to ensure a realistic machine results. It will have impact on future patient treatment, in that significant benefits are anticipated from this treatment modality.
Further details:
http://tinyurl.com/l92j6yl
More Information:http://tinyurl.com/l92j6yl
Experiments:Simulation plus experiments at CERN and Daresbury Lab.
Deadline: 2017-08-31
Region: Europe
Job description:
Treatment planning for VHEE (Very High Energy Electron) Scanned Beams
VHEE embraces the energy range 50 – 250 MeV and can deliver doses up to 20-30 Gy per second. Studies by DesRosiers, et al in the early 2000s have shown that VHEE therapy has the potential to be a better, yet cost-effective alternative to the photon therapy. Some potential advantages of this mode of radiotherapy over photon and proton therapy include:
· Better sculpting or conformal mapping –as there are minimal moving parts with electron scanning and beam steering is continuous.
· Rapid dose delivery –reduces necessity of preventing patient motion. In essence, physiological motion is frozen with this method –and indeed freezing the motion to less than one heartbeat should be feasible.
· Potentially better tumour control efficiency for the same dose.
· “Flash” therapy, entailing rapid and high dose delivered with VHEE beams indicates superior cell recovery –compared to that with cells irradiated over longer periods with extant modalities.
· Recent simulations with 15 MeV photons showed significant perturbations of dose around an air cavity in the tissue, whereas simulations with 200 MeV electron beams showed negligibly small perturbations.
VHEE radiotherapy will make a significant impact on treating cancer with radiotherapy and hence will improve the overall quality of life of the people within the UK. The treatment planning envisaged will entails detailed studies with realistic margins considered. It is anticipated to lead to high quality publications in this area, and to pave the way for the potential for a new treatment modality –with significant advantages of extant treatments. In addition to its direct impact on dose delivery studies, it will also have a significant impact on the design of a future linac-based machine for VHEE radiotherapy treatment –with the results of this study providing guidance on the requirement on a the design of a future machine suitable for patient treatment.
In summary, we anticipate major impact from this project in the area of high quality journal publications, cross-disciplinary work, and providing essential input into guiding the design of a future facility to ensure a realistic machine results. It will have impact on future patient treatment, in that significant benefits are anticipated from this treatment modality.
Further details:
http://tinyurl.com/l92j6yl
More Information:http://tinyurl.com/l92j6yl